Post-doctoral researcher (m/f/d)

Primary Duties & Responsibilities:

• Make key contributions to the ERC Starting Grant funded project “PerturbPhos” (Grant agreement ID: 101222284), developing ultra-sensitive mass spectrometry (MS)-based phosphoproteomics technologies to study how drugs affect a patient's tumor proteome
• Build and optimize a scalable phosphoproteomics platform tailored to high-dimensional perturbation experiments of primary cells
• Analyze large-scale (phospho)proteomics datasets using R or Python-based computational tools to integrate prior knowledge and characterize drug-induced phosphorylation changes
• Work and communicate efficiently across inter-professional teams
• Disseminate project results through presentations and manuscripts.

Required Skills & Qualifications:

• PhD in (bio)chemistry, molecular biology, systems biology, or a related field
• Theoretical knowledge and practical skills in mass spectrometry-based proteomics, ideally with hands-on experience in low-input phosphoproteomics
• Demonstrated experience with mammalian cell culture and sample preparation for MS analysis
• Ability to independently develop and troubleshoot MS-based proteomics workflows
• Prior experience with clinical patient material and/or characterizing small molecule drugs is desired
• Proficiency in R or Python for analyzing omics datasets, including statistical analysis and integration of multiple datatypes
• Strong track record of scientific excellence (e.g., high-quality first-author publications), rigorous research practice, and commitment to research integrity
• Strong ability work and communicate effectively in interdisciplinary teams (clinicians, biologists, bioinformaticians)
• Strong scientific writing and presentation skills in English.

We offer you even more:

• Classification is based on TV-L in pay grade E13 if the personal and collective agreement requirements are met.

Reference number: DM20/2026

* Limited to 24 months, with an option to extend

Regardless of origin, age, gender or disability - you are welcome here at Jena University Hospital.